Epigenetic Age Analysis Service

What is the DNAge Epigenetic Clock

Aging is the largest risk factor for many chronic diseases including cancer, cardiovascular disease, arthritis, osteoporosis, and type 2 diabetes. Therefore, quantifying the biological age is a fundamental step of understanding diseases and designing anti-aging intervention. Dr. Steve Horvath's epigenetic clock, the gold standard of aging clocks, predicts biological age by measuring DNA methylation at multiple sites [1, 2].

Accelerated epigenetic age has been associated with a lot of age-related conditions and diseases by independent research studies such as certain types of cancer [3, 4], obesity [5] and frailty [6]. Recently, a small clinical trial showed that the epigenetic clock, in agreement with the immunological and thymic measurements, could be turned back by a 3-part treatment cocktail. This indicates the power of epigenetic clock in identifying the effectiveness of anti-aging intervention on an accelerated timescale [7].