From Sample Collection to NGS: Find the Right Solution for Your Needs

Sample Collection

Sample Type	Target Nucleic Acid	Collection Volume	Sample Collection Device
Saliva	DNA/RNA	2 mL	Safe Collect - Saliva Collection
Fecal	DNA/RNA	1 mL or 1 g	Fecal Collection Tube
Urine	DNA/RNA	--	Urine Collection Buffer
Buccal	DNA/RNA	2 mL	Swab Collection Tube
Phenol RNA	RNA	--	TRI Reagent
Blood	DNA/RNA	3 mL	Blood Collection Tube
General Samples	DNA/RNA	--	DNA/RNA Shield

Optimized for Automation

Achieve reliability in genetics, diagnostics, forensics, and more with Zymo Research's automation-ready sample collection devices.

Preserve Sample Integrity with DNA/RNA Shield

Elevate your research with Zymo Research's industry-leading transport and storage medium, DNA/RNA Shield.

Fully Customizable

Tailor your sample collection device to your exact needs with custom barcoding, labeling, and more to streamline your workflow.

Nucleic Acid Extraction

Zymo Research offers a wide variety of kits for automated DNA, RNA, and total nucleic acid extractions. Our chemistries allow for versatile solutions across any sample type you need.

General Nucleic Acid Extraction

Microbial Studies

Liquid Biopsy (cell free)

RNA Extraction (Stored in TRI Reagent)

Purification & Clean-up

Plasmid

DNA Methylation

General Nucleic Acid Extraction - Quick Kits

For Sample Types: Blood, Plasma, Serum, Plant Cells, Cultured Cells

Target Nucleic Acid	Nucleic Acid Extraction Kit	Kit Size (preps)	Time on Deck*
gDNA / DNA	Quick-DNA Magbead Plus	1 x 96 / 4 x 96	< 175 min
RNA Total / RNA	Quick-RNA Magbead Plus	1 x 96 / 4 x 96	< 225 min
Total Nucleic Acid	Quick-DNA/RNA Magbead	1 x 96 / 4 x 96	< 400 min

For Sample Types: Viruses

Target Nucleic Acid	Nucleic Acid Extraction Kit	Kit Size (preps)	Time on Deck*
Total Nucleic Acid	Quick-DNA/RNA Viral Magbead	250 / 1000	< 125 min

For Sample Types: Cultured Cells

Target Nucleic Acid	Nucleic Acid Extraction Kit	Kit Size (preps)	Time on Deck*
gDNA	Quick-DNA HMW Magbead	96	< 175 min

*Time on deck will vary depending on the specific instrument configuration.

Versatile Nucleic Acid Purification

Zymo Research's Quick Kit Family offers versatile nucleic acid purification assays optimized for automation.

High-Quality Outputs

Extract high-quality nucleic acid ready for various applications, including NGS, RT/PCR, hybridization, and more.

Microbial Studies - ZymoBIOMICS

For Sample Types: Microbes, Bacterial, Fungal, Protozoan, Algae, Viral Mitochondrial, Fungal, Biofilms, Water, Swabs, Saliva, Fecal, Soil

Target Nucleic Acid	Nucleic Acid Extraction Kit	Kit Size (preps)	Time on Deck*
DNA	ZymoBIOMICS 96 Magbead DNA	2 x 96	< 75 min
RNA	ZymoBIOMICS Magbead RNA	1 x 96 / 4 x 96	< 95 min
Total Nucleic Acid	ZymoBIOMICS Magbead DNA/RNA	1 x 96 / 4 x 96	< 170 min

*Time on deck will vary depending on the specific instrument configuration.

Precision Microbiome Analysis

Zymo Research's ZymoBIOMICS Kit Family offers versatile nucleic acid purification assays optimized for automation.

Unbiased DNA and RNA Extraction

Extract unbiased DNA and RNA, setting the stage for comprehensive microbiome profiling.

High-Throughput Efficiency

Extract unbiased DNA and RNA, setting the stage for comprehensive microbiome profiling.

Liquid Biopsy (cell free) - MAGicBead cfDNA Isolation

For Sample Types: Blood, Plasma, Serum, Urine, Cerebrospinal Fluid, Amniotic Fluid, Spent Cell Culture Media

Target Nucleic Acid	Nucleic Acid Extraction Kit	Kit Size (preps)	Time on Deck*
Cell-Free DNA	MAGicBead cfDNA Isolation	50	< 40 min

*Time on deck will vary depending on the specific instrument configuration.

Revolutionary MAGicBead Technology

Capture the magic with Zymo Research's novel MAGicBead technology.

Streamlined Workflow

Eliminate alcohol-based washing and drying steps, saving time and effort.

High-Yield Cell-Free DNA

Achieve the fastest and highest yield of cell-free DNA, ready for NGS, PCR, and more.

RNA Extraction (Stored in TRI Reagent) - Direct Zol

For Samples stored in TRI Reagent

Target Nucleic Acid	Nucleic Acid Extraction Kit	Kit Size (preps)	Time on Deck*
RNA	Direct-zol-96 MagBead RNA	1 x 96 / 4 x 96	< 85 min

*Time on deck will vary depending on the specific instrument configuration.

Efficient High-Throughput RNA Isolation

The Direct-zol™-96 MagBead RNA kit is ready for high-throughput applications in RNA isolation.

Enhanced Safety & Workflow

Inactive viruses, bypass chloroform, streamline your process.

Versatile RNA Purity

Suitable for various RNA-based methods, including NGS, RT-PCR, hybridization, transcription profiling, and more.

Purification & Clean up - Clean & Concentrator

For Sample Types: PCR Products

Target Nucleic Acid	Nucleic Acid Extraction Kit	Kit Size (preps)	Time on Deck*
DNA	DNA Clean & Concentrator MagBead	96	< 50 min
RNA	RNA Clean & Concentrator MagBead	96	< 60 min

*Time on deck will vary depending on the specific instrument configuration.

Streamline High-Throughput Nucleic Acid Purification

Zymo Research's Clean & Concentrator kits offer a simple and reliable method for rapidly purifying extracted nucleic acids.

Plasmid - Zyppy - 96 Plasmid MagBead Miniprep

For Sample Types: Cultured Cells

Target Nucleic Acid	Nucleic Acid Extraction Kit	Kit Size (preps)	Time on Deck*
Plasmid DNA	Zyppy-96 Plasmid Magbead MiniPrep	96	< 75 min

*Time on deck will vary depending on the specific instrument configuration.

Fast High-Throughput Plasmid DNA Isolation

The Zyppy-96 Plasmid MagBead Miniprep is the fastest high-throughput (96-well) Pellet-Free plasmid DNA kit for efficient isolation of plasmid DNA from E.coli.

Streamlined Process

Features a modified alkaline lysis system that eliminates tedious centrifugation, pelleting, and re-suspension steps common in conventional procedures.

High-Quality Endotoxin-Free DNA

Eluted plasmid DNA is of the highest quality, endotoxin-free, and ideal for sensitive downstream applications, including restriction endonuclease digestion, DNA ligation, PCR, transcription, sequencing, and transfection.

DNA Methylation - EZ DNA Methylation

For Sample Types: Purified genomic DNA, endonuclease-digested DNA, linearized plasmid DNA

Target Nucleic Acid	Nucleic Acid Extraction Kit	Kit Size (preps)	Time on Deck*
gDNA	EZ-96 DNA Methylation-Lightning MagPrep	1 x 96/ 4 x 96 / 8 x 96	< 80 min

*Time on deck will vary depending on the specific instrument configuration.

Simplified Bisulfite Conversion

Zymo Research's EZ DNA Methylation Kits offer a simplified procedure for streamlined bisulfite treatment of DNA.

Minimized DNA Loss

Innovative desulphonation technologies reduce template degradation and DNA loss during treatment and cleanup.

Ideal for Downstream Analyses

Purified, converted DNA is suitable for PCR amplicfication and downstream analyses, including endonuclease digestion, sequencing, microarrays, and more.

Recommended for Illumina's Assays

These bisulfite conversion kits are recommended for use with Illumina's GoldenGate® and Infinium® Assays.

Application Assays

Zymo Research offers assays that address a wide variety of post-extraction applications, ensuring you have a complete, automated solution at your disposal.

RNA Analysis

Epigenetics

Metagenomics

PCR/rt-PCR

RNA Analysis

Complete your RNA workflow with one of Zymo Research's simple library kits. These kits feature novel technology and simple protocols, and are Automation-friendly.

Analysis Target	Application Kit
Depletion-based Total RNA Sequencing	Zymo-Seq RiboFree Total RNA Library Kit

Epigenetics

Complete your epigenetics solution with industry-leading chemistry that leads to reliable, precise analysis.

Analysis Target	Application Kit
Chromatin Footprinting	Zymo-Seq ATAC Library Kit
Cell-Free DNA Whole Genome Bisulfite Sequencing	Zymo-Seq Trio WBGS Library Kit
DNA Whole Genome Bisulfite Sequencing	Zymo-Seq WGBS Library Kit
Low-Input Whole Genome Bisulfite Sequencing	Pico Methyl-Seq Library Prep Kit
5-hmC NGS	RRHP 5-hmC Library Prep Kit
RRBS	Zymo-Seq RRBS Library Kit

Metagenomics

Zymo Research has developed unique NGS library prep kits and other library preparation methods that feature easy-to-use, streamlined workflows to generate ready-to-sequence libraries compatible with Illumina® - based sequencing chemistries.

Analysis Target	Application Kit
ITS Sequencing (Fungus)	Quick-ITS Plus NGS Library Prep Kit
16S Sequencing (Bacteria)	Quick-16S Plus NGS Library Prep Kit

PCR/rt - PCR

PCR and rt-PCR chemistries for specific target amplification and downstream detection by standard gel or quantitative instruments.

Analysis Target	Application Kit
PCR/qPCR	ZymoTag PreMix
rt-PCR	ZymoScript RT PreMix Kit

How can we help you today? Our team is here for you.

If you need help finding your solution or if you need FREE scripts for your platform, please reach out to us today!

Zymo Research Automation provides full support and consultations for the development and implementation of your automation workflow on platforms produced by Opentrons. These platforms include but are not limited to Opentrons OT-2 and Opentrons Flex. We have both free scripts and support material available for these platforms by Opentrons. We provide consultation that helps tailor a workflow solution to address all your needs from sample collection, through extraction, to downstream application and analysis. Free trial kits are available for validation.

Zymo Research Automation offers support and products for complete, turn-key, high-throughput laboratory automation solutions that address a wide range of sample types. These sample types include tissue samples, FFPE, insects, fungus, seeds, plant tissue, saliva, stool, buccal, urine, whole blood, TRIzol, Eukaryotic cells, bacterial cells, plant cells, yeast, buffy coat, lymphocytes, wastewater, soil, swabs, plasma, serum, milk, and more. Automation-ready extraction kits can target general groups such as DNA, RNA, total nucleic acid (TNA), and both fractional nucleic acid (DNA and RNA separate), with specific targets including cell-free, high-molecular-weight DNA, microbial DNA and/or RNA, micro-RNA, and viral nucleic acid. All these kits provide an extract that is ready for use in NGS, PCR, rtPCR, and qPCR methods that can be applied to DNA Methylation, Chromatin Analysis, Fungal Sequencing, Microbial Sequencing, RNA Sequencing, and Plasmid Transformation, among others. We offer trusted solutions for various industries ranging from academic research, clinical research, diagnostics laboratories, environmental science, wastewater surveillance, epidemiology, viral detection, pathogen detection, epigenetics, microbiome research and diagnostics, food and beverage, FDA, NASA, and other government agencies.